Flavonoids activity determination of ginkgo sample using electrochemical method

The determination of flavonoids activity is very important for drug effect evaluation. In this work, we proposed an advanced hydrogel based electrochemical approach for the quick determination flavonoids activity in plant extract. Zinc ions and chitosan have been used as raw materials for hydrogel synthesis. Then, the presence of the hydroxy radicals can initiate the depolymerization process. The presence of the flavonoids can delay the depolymerization and consequently used for determining their activity. We used ginkgo leaf extract as an example, demonstrated the successful preparation of the hydrogel platform and showed potential application in flavonoids activity determination.

Keywords: Electrochemical sensing; Flavonoids activity; Ginkgo extracts; Hydrogel; Crosslinking.