In this paper, a thermodynamic analysis and an exergoeconomic analysis are applied to vapor compression refrigeration cycle with refrigerant HFC-134a. The thermodynamics properties of the each stated of the system have been calculated and a parametric analysis of the coefficient of performance, the exergetic efficiency, the power input to the compressor and the mass flow rate of HFC-134a is realized for a given refrigeration capacity. The productive structure of the equipment of the system is generated in addition an exergoeconomics analysis is made, obtaining the resources, products and the irreversibilities of each equipment, the exergetic operation cost and the exergoeconomics operation cost are evaluated in function of the environmental temperature and the refrigerated spaced temperature. For the Mexican Republic, the variation of environment temperature is of 20ºC to 35ºC in average, for example, for this interval of temperatures and atmospheric pressure of 1 bar, refrigerated spaced temperature of -5ºC and for a refrigeration capacity of 5 TR, the coefficient of performance of the refrigeration cycle is 6.5 to 4, the exergetic efficiency is 49 to 30%, the exergetic operation cost is 4.5 to 10 kW and the exergoeconomic operation cost is 3.7 to 8.5 $/hr.