Ultrasound-assisted extraction (UAE) of carbohydrates from powdered sotol plant (Dasylirion wheeleri) at different ultrasonic powers (UPs) (32.13–85.9 W) and temperatures (20.85–49.14 °C), in a 1:24 sotol:water ratio for 10 min was evaluated; a treatment control was done under thermal-traditional extraction. Total carbohydrates (TC), reducing sugars (RS), total fructan (FRU), glucose, fructose content, and average polymerization degree (DPn) were evaluated. Fructan extraction kinetics and mass transfer coefficients (KL) were calculated. RS and TC were significantly affected (P < 0.05) by temperature; FRU, by UP. Glucose, fructose, DPn,and KL were affected (P < 0.05) by UP and temperature. TC and FRU reached maximum values ​​at 54–59.0 W and 36.0 °C. KL ​reached a maximum at 55 W and 33.5 °C. The opposite trend was observed for glucose and fructose, presenting minimum values under these conditions, indicating minimal fructan damage. Under these conditions, DPn values ranged from 4.18 to 4.7 with maximum FRU of 7.97 g×100 g-1 sotol d.m. Thermal treatment led to higher release of TC and RS and lower DPn compared with UAE, but showed similar FRU. UAE (54–59.05 W at 36.0 °C) can be used to obtain FRU from sotol heads.