In this work the kinetics parameters of degradation of MTBE with persulfate catalyzed by Ag+ ions in aqueous solution at different temperatures and different concentrations of the oxidizing agent and catalyst, were determined. The experimental results indicate that the reaction is much faster in the presence of Ag+ ions. The Arrhenius activation energy for the catalyzed reaction is 69.89 x 103 J mol-1 (1.14 mol m-3 MTBE, 25.00 mol m-3 Na2S2O8, 0.30 mol m-3 Ag+), whereas in the uncatalyzed reaction is 105.61 x 103 J mol-1 (1.14 mol m-3 MTBE, 25.00 mol m-3 Na2S2O8) in the temperature range of 20 to 40 °C. The findings in this research stated the fundamentals for a novel wastewater treatment.